In a new study, researchers at the Department of Biochemistry, Indian Institute of Science (IISc), have used a novel imaging technique to pinpoint how strongly adjacent bases – the building blocks of ...

As one of the inventors of next-generation DNA sequencing, Sir Shankar Balasubramanian could claim to be responsible for a revolution in the life sciences. Balasubramanian and chemist David Klenerman, ...

Nearly four decades after biochemist Phoebus Levene first postulated his "tetranucleotide hypothesis" in 1910, most scientists still believed that DNA was made up of equal numbers of the four ...

All life on Earth rests on the same foundation: a four-letter genetic alphabet spelling out a repertoire of three-letter words that specify 20 amino acids. These basic building blocks—the components ...

The DNA of some viruses doesn’t use the same four nucleotide bases found in all other life. New work shows how this exception is possible and hints that it could be more common than we think. All life ...