UNIVERISTY PARK, Pa. — The tumor suppressor protein p53, known as "the guardian of the genome," protects the body’s DNA from daily stress or long-term damage by triggering the cells to make repairs or ...

The simplest explanation of cancer is that, for any reason, a cell in our body ignores its biological program and gets loose, multiplying itself again and again, creating a tumour. This has a lot to ...

In the 1970s, scientists knew that some viruses and chemicals caused cancer, but they didn’t know how. Arnold Levine, a biologist currently at the Institute for Advanced Study researched DNA viruses ...

A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled "Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells." Researchers ...

A new study has, for the first time, settled the debate about how a mutated protein present in half of all human cancers drives tumor growth. The discovery will not only facilitate a rethink of the ...

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this ...

The study of mutant p53 isoforms lies at the forefront of cancer biology, revealing the profound impact of TP53 gene alterations on tumor progression and ...