Over the past 10 years, CRISPR has been transformative for research, enabling gene editing that is fast, simple and precise, experts say. The first paper showing that CRISPR could be used to edit the ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

Scientists had tried to treat diseases by editing genes since the 1990s, but the methods were cumbersome and didn’t pay off. Then in June 2012, the journal Science published a paper by two future ...

In the world of biopharmaceutical innovation, 2024 will be remembered as CRISPR’s breakout year. In the spring, five patients with sickle cell disease began treatment with Casgevy, the first ...

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Northwestern scientists have developed a new nanostructure that supercharges CRISPR’s ability to safely and efficiently enter cells, potentially unlocking its full power to treat genetic diseases. By ...

Jimi Olaghere used to end up in the emergency room so often that the hospital reserved a bed for him. Sickle cell disease dominated his life. A genetic defect he was born with meant that instead of ...

CAR T cell therapy, often referred to as a “living drug,” has successfully treated blood cancers such as leukemia and lymphoma. The approach, which was pioneered at Memorial Sloan Kettering Cancer ...

The FDA late last week set for December a groundbreaking decision on whether to grant its first-ever approval for a CRISPR-Cas9 gene-edited therapy—but the milestone so far doesn’t seem to be wowing ...

An explanation of how the cutting-edge gene editing tool works.